Q&A

01 Gut Health - Prebiotic Function Activation
As prebiotics, HMOs resist degradation by stomach acid and digestive enzymes, reaching the large intestine intact. Their structural complexity allows selective utilization by different gut microbes.

02 Immune Health - Growth Shield
HMOs provide immune protection through four mechanisms: regulating gut flora, inhibiting pathogen adhesion, improving intestinal barrier function, and direct immune modulation. CABIO's study on healthy mice showed that 2'-FL supplementation significantly enhances immunity:

03 Brain Health - Seizing the Developmental Window
Breastfeeding is closely linked to early neurodevelopment, with HMOs potentially accelerating myelination via the "gut-brain axis" by regulating the production of neuroactive bacterial metabolites (e.g., SCFAs, GABA, serotonin).

CABIO's algal oil DHA (CABIO-A-2) has obtained China's New Food Ingredient certification, US FDA GRAS (Generally Recognized As Safe) status, US organic certification, and EU market access (Novel Food authorization). Its ARA (arachidonic acid) has also secured GRAS in the US and Novel Food approval in the EU. In August 2024, CABIO's first product via biosynthetic method – 2'-fucosyllactose (2'-FL) – was officially approved by the National Health Commission (NHC) and obtained a Food Production License.

CABIO has initiated application research in infant formula and foods for special medical purposes, while concurrently conducting functional studies on various HMOs (human milk oligosaccharides) in gut microecology, brain development, and special diseases. The company continues to advance R&D and industrial production of LNnT, 3-FL, 3'-SL, 6'-SL, and other HMOs, supporting the upgrading of infant formula and nutritional health industries.

CABIO's algal oil DHA strain is extracted from Schizochytrium sp. The company's strain management team is responsible for preserving production strains, which are inoculated into fermenters containing sterile culture media for expanded fermentation. DHA-rich oils accumulate within microalgal cells, and finally, microbial oils are obtained through enzymatic extraction from the cells. Schizochytrium sp. is one of the microalgae species approved by China's National Health Commission for DHA production. Notably, CABIO's algal oil DHA strains are self-preserved and expanded in-house, rather than harvested from marine algae.

CABIO's main products currently include polyunsaturated fatty acids such as arachidonic acid (ARA) and docosahexaenoic acid (DHA), terpenoids like β-carotene (BC) and astaxanthin (AST), as well as carbohydrate-based substances such as N-acetylneuraminic acid (SA) and human milk oligosaccharides (HMOs). These products are primarily available in the forms of oils and microcapsules (powders).

CABIO's products are widely applied in infant formula, functional foods, dietary supplements, foods for special medical purposes, animal nutrition, personal care, cosmetics and other fields.

(A) Promotes Brain Development
Sialic acid, a brain nutrient acting on cell membranes and synapses, supports memory and intellectual development, and increases the expression of learning-related genes in infants. Therefore, adding sialic acid to maternal and infant formula plays a crucial role in ensuring normal infant growth and development.

Additionally, sialic acid is proven to be closely related to the protection of brain neurons[6]. Enzyme extracts of sialic acid help prevent or delay the gradual loss of neuronal structure or function, combating neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD), and Huntington's disease (HD).
(B) Helps Brighten Skin Tone and Anti-Aging
Studies have found that sialic acid can work synergistically with other whitening components to brighten skin tone and block melanin production. It also plays a positive role in improving skin texture, enhancing the skin barrier, slowing down aging, and promoting collagen synthesis, making it an ideal additive for beauty products.
(C) Other Functions
Reported bioactivities of sialic acid also include anti-inflammatory, anti-influenza virus, immune regulation, lowering blood lipid levels, improving bone strength, and regulating hormone content, etc..

In terms of intestinal health, sialic acid inhibits harmful bacteria and promotes the growth of probiotics, thereby enhancing human metabolism.

Furthermore, a 2024 patent from CABIO shows that sialic acid can reduce and inhibit weight gain, contributing to the fight against overweight, obesity, and related complications.

A dietary supplement is made primarily from vitamins, mineral substances and extracts with a comparatively clear structure-activity relationship (SAR). Oral intake of nutrients and bioactive substances essential to the body can improve health and lower down disease risks.

Early life is a vital period that determines one's lifelong health. It underpins the physique growth and brain development of fetuses and infants, with a lifelong impact on physical ability and neuropsychological potential.